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A Prospective Study of Dieatry Folate and Vitamin B and Colon Cancer According to MSI and KRAS Mutational Status

Sporadic microsatellite instability-high (MSI-high) colon cancers are positively associated with MLH1 promoter methylation, and inversely with KRAS mutation. One-carbon metabolism is critical for methylation reactions and nucleotide biosynthesis, but the influence of dietary one-carbon nutrients suc...

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Bibliografiska uppgifter
Huvudupphovsmän: Schernhammer, Eva S., Giovannuccci, Edward, Fuchs, Charles S., Ogino, Shuji
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741404/
https://ncbi.nlm.nih.gov/pubmed/18843035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-08-0638
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