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Species and Gender Differences Affect the Metabolism of Emodin via Glucuronidation
The aim of the present study was to define the mechanisms responsible for poor bioavailability of emodin by determining its metabolism using in vitro and in situ disposition models of the intestine and liver. Liver microsomes of mice, rats, guinea pigs, dogs, and humans were used along with the rat...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895442/ https://ncbi.nlm.nih.gov/pubmed/20467923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9200-6 |
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