Pulmonary Immunization Using Antigen 85-B Polymeric Microparticles to Boost Tuberculosis Immunity

This study aims to evaluate immunization with polymeric microparticles containing recombinant antigen 85B (rAg85B) delivered directly to the lungs to protect against tuberculosis. rAg85B was expressed in Escherichia coli and encapsulated in poly(lactic-co-glycolic acid) microparticles (P-rAg85B). Th...

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Autores principales: Lu, Dongmei, Garcia-Contreras, Lucila, Muttil, Pavan, Padilla, Danielle, Xu, Ding, Liu, Jian, Braunstein, Miriam, McMurray, David N., Hickey, Anthony James
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895436/
https://ncbi.nlm.nih.gov/pubmed/20422340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9193-1
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