Pulmonary Immunization Using Antigen 85-B Polymeric Microparticles to Boost Tuberculosis Immunity

This study aims to evaluate immunization with polymeric microparticles containing recombinant antigen 85B (rAg85B) delivered directly to the lungs to protect against tuberculosis. rAg85B was expressed in Escherichia coli and encapsulated in poly(lactic-co-glycolic acid) microparticles (P-rAg85B). Th...

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Detalhes bibliográficos
Main Authors: Lu, Dongmei, Garcia-Contreras, Lucila, Muttil, Pavan, Padilla, Danielle, Xu, Ding, Liu, Jian, Braunstein, Miriam, McMurray, David N., Hickey, Anthony James
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895436/
https://ncbi.nlm.nih.gov/pubmed/20422340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9193-1
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