Apparent Tradeoff of Higher Activity in MMP-12 for Enhanced Stability and Flexibility in MMP-3

The greater activity of MMP-12 than MMP-3 toward substrates from protein fibrils has been quantified. Why is MMP-12 the more active protease? We looked for behaviors associated with the higher activity of MMP-12 than MMP-3, using nuclear magnetic resonance to monitor backbone dynamics and residue-sp...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Liang, Xiangyang, Arunima, A., Zhao, Yingchu, Bhaskaran, Rajagopalan, Shende, Anuradha, Byrne, Todd S., Fleeks, Jeremy, Palmier, Mark O., Van Doren, Steven R.
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2010
Предметы:
Protein
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895380/
https://ncbi.nlm.nih.gov/pubmed/20655856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.002
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы