Apparent Tradeoff of Higher Activity in MMP-12 for Enhanced Stability and Flexibility in MMP-3

The greater activity of MMP-12 than MMP-3 toward substrates from protein fibrils has been quantified. Why is MMP-12 the more active protease? We looked for behaviors associated with the higher activity of MMP-12 than MMP-3, using nuclear magnetic resonance to monitor backbone dynamics and residue-sp...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Liang, Xiangyang, Arunima, A., Zhao, Yingchu, Bhaskaran, Rajagopalan, Shende, Anuradha, Byrne, Todd S., Fleeks, Jeremy, Palmier, Mark O., Van Doren, Steven R.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2010
Fag:
Protein
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895380/
https://ncbi.nlm.nih.gov/pubmed/20655856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.002
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker