Blockage of Anthrax PA63 Pore by a Multicharged High-Affinity Toxin Inhibitor

Single channels of Bacillus anthracis protective antigen, PA(63), were reconstituted into planar lipid membranes and their inhibition by cationic aminopropylthio-β-cyclodextrin, AmPrβCD, was studied. The design of the highly efficient inhibitor, the sevenfold symmetrical cyclodextrin molecule chemic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nestorovich, Ekaterina M., Karginov, Vladimir A., Berezhkovskii, Alexander M., Bezrukov, Sergey M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2010
Pynciau:
Channels and Transporters
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895364/
https://ncbi.nlm.nih.gov/pubmed/20655841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.070
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