Blockage of Anthrax PA63 Pore by a Multicharged High-Affinity Toxin Inhibitor

Single channels of Bacillus anthracis protective antigen, PA(63), were reconstituted into planar lipid membranes and their inhibition by cationic aminopropylthio-β-cyclodextrin, AmPrβCD, was studied. The design of the highly efficient inhibitor, the sevenfold symmetrical cyclodextrin molecule chemic...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Nestorovich, Ekaterina M., Karginov, Vladimir A., Berezhkovskii, Alexander M., Bezrukov, Sergey M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2010
Materias:
Channels and Transporters
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895364/
https://ncbi.nlm.nih.gov/pubmed/20655841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.070
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares