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Blockage of Anthrax PA63 Pore by a Multicharged High-Affinity Toxin Inhibitor
Single channels of Bacillus anthracis protective antigen, PA(63), were reconstituted into planar lipid membranes and their inhibition by cationic aminopropylthio-β-cyclodextrin, AmPrβCD, was studied. The design of the highly efficient inhibitor, the sevenfold symmetrical cyclodextrin molecule chemic...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Biophysical Society
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895364/ https://ncbi.nlm.nih.gov/pubmed/20655841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.070 |
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