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Hysteresis in the Cell Response to Time-Dependent Substrate Stiffness

Mechanical cues like the rigidity of the substrate are main determinants for the decision-making of adherent cells. Here we use a mechano-chemical model to predict the cellular response to varying substrate stiffnesses. The model equations combine the mechanics of contractile actin filament bundles...

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Detalles Bibliográficos
Main Authors: Besser, Achim, Schwarz, Ulrich S.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895361/
https://ncbi.nlm.nih.gov/pubmed/20655823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.008
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