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Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility

The mechanical microenvironment is known to influence single-cell migration; however, the extent to which mechanical cues affect collective migration of adherent cells is not well understood. We measured the effects of varying substrate compliance on individual cell migratory properties in an epithe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ng, Mei Rosa, Besser, Achim, Danuser, Gaudenz, Brugge, Joan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483134/
https://ncbi.nlm.nih.gov/pubmed/23091067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201207148
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