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Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility

The mechanical microenvironment is known to influence single-cell migration; however, the extent to which mechanical cues affect collective migration of adherent cells is not well understood. We measured the effects of varying substrate compliance on individual cell migratory properties in an epithe...

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Detalhes bibliográficos
Main Authors: Ng, Mei Rosa, Besser, Achim, Danuser, Gaudenz, Brugge, Joan S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483134/
https://ncbi.nlm.nih.gov/pubmed/23091067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201207148
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