INCREASED NEUROSTEROID SENSITIVITY OF HIPPOCAMPAL GABA(A) RECEPTORS DURING POSTNATAL DEVELOPMENT

To investigate developmental changes in neuro-steroid modulation of GABA(A) receptors, whole-cell currents were elicited by applying GABA with allopregnanolone or pregnenolone sulfate (PS) to dentate granule cells (DGCs), acutely isolated from 7–14-day-old and adult rats. GABA evoked larger currents...

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Main Authors: MTCHEDLISHVILI, Z., SUN, C. S., HARRISON, M. B., KAPUR, J.
Formato: Artigo
Idioma:Inglês
Publicado: 2003
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895320/
https://ncbi.nlm.nih.gov/pubmed/12710974
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