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Similarities between Argonautes and the alpha-sarcin-like ribotoxins: Implications for microRNA action

We report structural, functional, and biochemical similarities between Argonautes, the effector proteins of RNA-induced silencing complexes (RISCs), and alpha-sarcin-like ribotoxins. At the structural level, regions of similarity in the amino acid sequence are located in protein loops both in the ri...

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Detalhes bibliográficos
Main Authors: Pichinuk, Edward, Wreschner, Daniel H
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895252/
https://ncbi.nlm.nih.gov/pubmed/20512980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.391
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