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The ribotoxin α-sarcin can cleave the sarcin/ricin loop on late 60S pre-ribosomes
The ribotoxin α-sarcin belongs to a family of ribonucleases that cleave the sarcin/ricin loop (SRL), a critical functional rRNA element within the large ribosomal subunit (60S), thereby abolishing translation. Whether α-sarcin targets the SRL only in mature 60S subunits remains unresolved. Here, we...
Shranjeno v:
| izdano v: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7293039/ https://ncbi.nlm.nih.gov/pubmed/32365182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa315 |
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