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The Prp19 complex and the Usp4(Sart3) deubiquitinating enzyme control reversible ubiquitination at the spliceosome
The spliceosome, a dynamic assembly of proteins and RNAs, catalyzes the excision of intron sequences from nascent mRNAs. Recent work has suggested that the activity and composition of the spliceosome are regulated by ubiquitination, but the underlying mechanisms have not been elucidated. Here, we re...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895201/ https://ncbi.nlm.nih.gov/pubmed/20595234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1925010 |
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