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The Prp19 complex and the Usp4(Sart3) deubiquitinating enzyme control reversible ubiquitination at the spliceosome

The spliceosome, a dynamic assembly of proteins and RNAs, catalyzes the excision of intron sequences from nascent mRNAs. Recent work has suggested that the activity and composition of the spliceosome are regulated by ubiquitination, but the underlying mechanisms have not been elucidated. Here, we re...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Song, Eun Joo, Werner, Shannon L., Neubauer, Jakob, Stegmeier, Frank, Aspden, Julie, Rio, Donald, Harper, J. Wade, Elledge, Stephen J., Kirschner, Marc W., Rape, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895201/
https://ncbi.nlm.nih.gov/pubmed/20595234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1925010
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