USP15 regulates dynamic protein–protein interactions of the spliceosome through deubiquitination of PRP31

Post-translational modifications contribute to the spliceosome dynamics by facilitating the physical rearrangements of the spliceosome. Here, we report USP15, a deubiquitinating enzyme, as a regulator of protein–protein interactions for the spliceosome dynamics. We show that PRP31, a component of U4...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Das, Tanuza, Park, Joon Kyu, Park, Jinyoung, Kim, Eunji, Rape, Michael, Kim, Eunice EunKyeong, Song, Eun Joo
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416801/
https://ncbi.nlm.nih.gov/pubmed/28088760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1365
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