The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin

The origin recognition complex (ORC) binds to the specific positions on chromosomes that serve as DNA replication origins. Although ORC is conserved from yeast to humans, the DNA sequence elements that specify ORC binding are not. In particular, metazoan ORC shows no obvious DNA sequence specificity...

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Hlavní autoři: Müller, Philipp, Park, Sookhee, Shor, Erika, Huebert, Dana J., Warren, Christopher L., Ansari, Aseem Z., Weinreich, Michael, Eaton, Matthew L., MacAlpine, David M., Fox, Catherine A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2010
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895200/
https://ncbi.nlm.nih.gov/pubmed/20595233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1906410
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