The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin

The origin recognition complex (ORC) binds to the specific positions on chromosomes that serve as DNA replication origins. Although ORC is conserved from yeast to humans, the DNA sequence elements that specify ORC binding are not. In particular, metazoan ORC shows no obvious DNA sequence specificity...

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Detalhes bibliográficos
Main Authors: Müller, Philipp, Park, Sookhee, Shor, Erika, Huebert, Dana J., Warren, Christopher L., Ansari, Aseem Z., Weinreich, Michael, Eaton, Matthew L., MacAlpine, David M., Fox, Catherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895200/
https://ncbi.nlm.nih.gov/pubmed/20595233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1906410
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