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The Effect of Rapamycin on Bone Growth in Rabbits

mTOR is a nutrient-sensing protein kinase that regulates numerous cellular processes. Our prior studies using the mTOR inhibitor, rapamycin, indicate an important role for mTOR in chondrogenesis. We extended our observations to a physiological, in vivo model of bone growth, direct infusion of rapamy...

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Detalhes bibliográficos
Main Authors: Phornphutkul, Chanika, Lee, Mark, Voigt, Cliff, Wu, Ke-Ying, Ehrlich, Michael G., Gruppuso, Philip A., Chen, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894807/
https://ncbi.nlm.nih.gov/pubmed/19382193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.20894
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