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The effect of rapamycin on DNA synthesis in multiple tissues from late gestation fetal and postnatal rats
Rapamycin is a potent antiproliferative agent that arrests cells in the G1 phase of the cell cycle through a variety of mechanisms involving the inhibition of the mammalian target of rapamycin (mTOR) pathway. The majority of normal cells in culture are sensitive to the cytostatic effects of rapamyci...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518428/ https://ncbi.nlm.nih.gov/pubmed/18550700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00450.2007 |
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