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Copy number variation and cytidine analogue cytotoxicity: A genome-wide association approach

BACKGROUND: The human genome displays extensive copy-number variation (CNV). Recent discoveries have shown that large segments of DNA, ranging in size from hundreds to thousands of nucleotides, are either deleted or duplicated. This CNV may encompass genes, leading to a change in phenotype, includin...

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Detalhes bibliográficos
Main Authors: Kalari, Krishna R, Hebbring, Scott J, Chai, High Seng, Li, Liang, Kocher, Jean-Pierre A, Wang, Liewei, Weinshilboum, Richard M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894803/
https://ncbi.nlm.nih.gov/pubmed/20525348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-357
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