HIV-1 Replication through hHR23A-Mediated Interaction of Vpr with 26S Proteasome

HIV-1 Vpr is a virion-associated protein. Its activities link to viral pathogenesis and disease progression of HIV-infected patients. In vitro, Vpr moderately activates HIV-1 replication in proliferating T cells, but it is required for efficient viral infection and replication in vivo in non-dividin...

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Detalhes bibliográficos
Main Authors: Li, Ge, Elder, Robert T., Dubrovsky, Larisa, Liang, Dong, Pushkarsky, Tatiana, Chiu, Karen, Fan, Tao, Sire, Josephine, Bukrinsky, Michael, Zhao, Richard Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894085/
https://ncbi.nlm.nih.gov/pubmed/20614012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011371
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