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hHR23B is required for genotoxic-specific activation of p53 and apoptosis
Rad23 proteins function in both DNA repair and protein stability regulation. As ubiquitinated forms of p53 are stabilized after DNA damage in concert with p53 functional activation, and human Rad23 proteins (hHR23A and B) regulate p53 stability in unstressed cells, the role of hHR23B in post-genotox...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1804095/ https://ncbi.nlm.nih.gov/pubmed/16924240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209865 |
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