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Altered Intra-Nuclear Organisation of Heterochromatin and Genes in ICF Syndrome

The ICF syndrome is a rare autosomal recessive disorder, the most common symptoms of which are immunodeficiency, facial anomalies and cytogenetic defects involving decondensation and instability of chromosome 1, 9 and 16 centromeric regions. ICF is also characterised by significant hypomethylation o...

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Detalhes bibliográficos
Main Authors: Jefferson, Andrew, Colella, Stefano, Moralli, Daniela, Wilson, Natalie, Yusuf, Mohammed, Gimelli, Giorgio, Ragoussis, Jiannis, Volpi, Emanuela V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894064/
https://ncbi.nlm.nih.gov/pubmed/20613881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011364
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