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HAC stability in murine cells is influenced by nuclear localization and chromatin organization
BACKGROUND: Human artificial chromosomes (HAC) are small functional extrachromosomal elements, which segregate correctly during each cell division. In human cells, they are mitotically stable, however when the HAC are transferred to murine cells they show an increased and variable rate of loss. In s...
में बचाया:
| मुख्य लेखकों: | , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2009
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674426/ https://ncbi.nlm.nih.gov/pubmed/19267891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-10-18 |
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