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TumorBoost: Normalization of allele-specific tumor copy numbers from a single pair of tumor-normal genotyping microarrays

BACKGROUND: High-throughput genotyping microarrays assess both total DNA copy number and allelic composition, which makes them a tool of choice for copy number studies in cancer, including total copy number and loss of heterozygosity (LOH) analyses. Even after state of the art preprocessing methods,...

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Detalhes bibliográficos
Main Authors: Bengtsson, Henrik, Neuvial, Pierre, Speed, Terence P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894037/
https://ncbi.nlm.nih.gov/pubmed/20462408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-245
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