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Parent-specific copy number in paired tumor–normal studies using circular binary segmentation
Motivation: High-throughput techniques facilitate the simultaneous measurement of DNA copy number at hundreds of thousands of sites on a genome. Older techniques allow measurement only of total copy number, the sum of the copy number contributions from the two parental chromosomes. Newer single nucl...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137217/ https://ncbi.nlm.nih.gov/pubmed/21666266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr329 |
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