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TBC-2 Regulates RAB-5/RAB-7-mediated Endosomal Trafficking in Caenorhabditis elegans

During endosome maturation the early endosomal Rab5 GTPase is replaced with the late endosomal Rab7 GTPase. It has been proposed that active Rab5 can recruit and activate Rab7, which in turn could inactivate and remove Rab5. However, many of the Rab5 and Rab7 regulators that mediate endosome maturat...

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Détails bibliographiques
Auteurs principaux: Chotard, Laëtitia, Mishra, Ashwini K., Sylvain, Marc-André, Tuck, Simon, Lambright, David G., Rocheleau, Christian E.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893991/
https://ncbi.nlm.nih.gov/pubmed/20462958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-11-0947
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