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Caenorhabditis elegans SAND-1 is essential for RAB-7 function in endosomal traffic

The small rab-GTPase RAB-7 acts in endosome and endosome to lysosome traffic. We identified SAND-1 as a protein required for RAB-7 function based on similarities between SAND-1 and RAB-7 RNAi phenotypes. Although the initial uptake of yolk protein in oocytes, or of soluble secreted (ss) GFP in coelo...

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Autori principali: Poteryaev, Dmitry, Fares, Hanna, Bowerman, Bruce, Spang, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783445/
https://ncbi.nlm.nih.gov/pubmed/17203072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601498
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