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Bcl2 is not required for the development and maintenance of leukemia stem cells in mice
The existence of leukemia stem cells (LSCs) responsible for tumor maintenance has been firmly established. Therefore, therapeutic targeting of these LSCs may have a profound impact on cancer eradication. The anti-apoptotic protein Bcl2 has been proposed as a therapeutic target, but its role in LSC b...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893797/ https://ncbi.nlm.nih.gov/pubmed/20299524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq062 |
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