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Spark-induced Sparks as a Mechanism of Intracellular Calcium Alternans in Cardiac Myocytes

RATIONALE: Intracellular calcium (Ca) alternans has been widely studied in cardiac myocytes and tissue, yet the underlying mechanism remains controversial. OBJECTIVE: In this study, we used computational modeling and simulation to study how randomly occurring Ca sparks interact collectively to resul...

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Détails bibliographiques
Auteurs principaux: Rovetti, Robert, Cui, Xiaohua, Garfinkel, Alan, Weiss, James N., Qu, Zhilin
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893409/
https://ncbi.nlm.nih.gov/pubmed/20378857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.213975
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