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Gene regulation and chromatin remodeling by IL-12 and Type I interferon in programming for CD8 T cell effector function and memory

A third signal that can be provided by IL-12 or Type I IFN is required for differentiation of naïve CD8 T cells responding to Ag and costimulation. The cytokines program development of function and memory within three days of initial stimulation, and we show here that programming involves regulation...

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Hlavní autoři: Agarwal, Pujya, Raghavan, Arvind, Nandiwada, Sarada L., Curtsinger, Julie M., Bohjanen, Paul R., Mueller, Daniel L., Mescher, Matthew F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893405/
https://ncbi.nlm.nih.gov/pubmed/19592655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900592
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