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Analysis of the Functional Consequences of Lethal Mutations in Mitochondrial Translational Elongation Factors

Mammalian mitochondria synthesize a set of thirteen proteins that are essential for energy generation via oxidative phosphorylation. The genes for all of the factors required for synthesis of the mitochondrially-encoded proteins are located in the nuclear genome. A number of disease-causing mutation...

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Bibliografische gegevens
Hoofdauteurs: Akama, Kenta, Christian, Brooke E., Jones, Christie N., Ueda, Takuya, Takeuchi, Nono, Spremulli, Linda L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893280/
https://ncbi.nlm.nih.gov/pubmed/20435138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2010.04.003
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