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Analysis of the Functional Consequences of Lethal Mutations in Mitochondrial Translational Elongation Factors
Mammalian mitochondria synthesize a set of thirteen proteins that are essential for energy generation via oxidative phosphorylation. The genes for all of the factors required for synthesis of the mitochondrially-encoded proteins are located in the nuclear genome. A number of disease-causing mutation...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893280/ https://ncbi.nlm.nih.gov/pubmed/20435138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2010.04.003 |
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