Unconventional decoding of the AUA codon as methionine by mitochondrial tRNA(Met) with the anticodon f(5)CAU as revealed with a mitochondrial in vitro translation system

Mitochondrial (mt) tRNA(Met) has the unusual modified nucleotide 5-formylcytidine (f(5)C) in the first position of the anticodon. This tRNA must translate both AUG and AUA as methionine. By constructing an in vitro translation system from bovine liver mitochondria, we examined the decoding propertie...

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Detalhes bibliográficos
Main Authors: Takemoto, Chie, Spremulli, Linda L., Benkowski, Lisa A., Ueda, Takuya, Yokogawa, Takashi, Watanabe, Kimitsuna
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655697/
https://ncbi.nlm.nih.gov/pubmed/19151083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp001
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