Unconventional decoding of the AUA codon as methionine by mitochondrial tRNA(Met) with the anticodon f(5)CAU as revealed with a mitochondrial in vitro translation system

Mitochondrial (mt) tRNA(Met) has the unusual modified nucleotide 5-formylcytidine (f(5)C) in the first position of the anticodon. This tRNA must translate both AUG and AUA as methionine. By constructing an in vitro translation system from bovine liver mitochondria, we examined the decoding propertie...

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Hlavní autoři: Takemoto, Chie, Spremulli, Linda L., Benkowski, Lisa A., Ueda, Takuya, Yokogawa, Takashi, Watanabe, Kimitsuna
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655697/
https://ncbi.nlm.nih.gov/pubmed/19151083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp001
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