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Influence of homologous recombinational repair on cell survival and chromosomal aberration induction during the cell cycle in γ-irradiated CHO cells

The repair of DNA double-strand breaks (DSB) by homologous recombinational repair (HRR) underlies the high radioresistance and low mutability observed in S-phase mammalian cells. To evaluate the contributions of HRR and nonhomologous end-joining (NHEJ) to overall DSB repair capacity throughout the c...

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Autori principali: Wilson, Paul F., Hinz, John M., Urbin, Salustra S., Nham, Peter B., Thompson, Larry H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893262/
https://ncbi.nlm.nih.gov/pubmed/20434408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.03.009
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