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RAD51D- and FANCG-dependent base substitution mutagenesis at the ATP1A1 locus in mammalian cells

Elaborate processes act at the DNA replication fork to minimize the generation of chromatid discontinuity when lesions are encountered. To prevent collapse of stalled replication forks, mutagenic translesion synthesis (TLS) polymerases are recruited temporarily to bypass DNA lesions. When a replicat...

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Bibliografski detalji
Glavni autori: Hinz, John M., Urbin, Salustra S., Thompson, Larry H.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692916/
https://ncbi.nlm.nih.gov/pubmed/19427512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2009.03.001
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