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RAD51D- and FANCG-dependent base substitution mutagenesis at the ATP1A1 locus in mammalian cells

Elaborate processes act at the DNA replication fork to minimize the generation of chromatid discontinuity when lesions are encountered. To prevent collapse of stalled replication forks, mutagenic translesion synthesis (TLS) polymerases are recruited temporarily to bypass DNA lesions. When a replicat...

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Détails bibliographiques
Auteurs principaux: Hinz, John M., Urbin, Salustra S., Thompson, Larry H.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692916/
https://ncbi.nlm.nih.gov/pubmed/19427512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2009.03.001
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