Disparate contributions of the Fanconi anemia pathway and homologous recombination in preventing spontaneous mutagenesis

Fanconi anemia (FA) is a chromosomal instability disorder in which DNA-damage processing defects are reported for translesion synthesis (TLS), non-homologous end joining (NHEJ) and homologous recombination (HR; both increased and decreased). To reconcile these diverse findings, we compared spontaneo...

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Autori principali: Hinz, John M., Nham, Peter B., Urbin, Salustra S., Jones, Irene M., Thompson, Larry H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2007
Soggetti:
Molecular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920256/
https://ncbi.nlm.nih.gov/pubmed/17517774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm315
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