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CONSERVED HELICASE DOMAIN OF HUMAN RECQ4 IS REQUIRED FOR STRAND ANNEALING-INDEPENDENT DNA UNWINDING

Humans have five members of the well conserved RecQ helicase family: RecQ1, Bloom syndrome protein (BLM), Werner syndrome protein (WRN), RecQ4, and RecQ5, which are all known for their roles in maintaining genome stability. BLM, WRN, and RecQ4 are associated with premature aging and cancer predispos...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rossi, Marie L., Ghosh, Avik K., Kulikowicz, Tomasz, Croteau, Deborah L., Bohr, Vilhelm A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893255/
https://ncbi.nlm.nih.gov/pubmed/20451470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.04.003
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