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CONSERVED HELICASE DOMAIN OF HUMAN RECQ4 IS REQUIRED FOR STRAND ANNEALING-INDEPENDENT DNA UNWINDING

Humans have five members of the well conserved RecQ helicase family: RecQ1, Bloom syndrome protein (BLM), Werner syndrome protein (WRN), RecQ4, and RecQ5, which are all known for their roles in maintaining genome stability. BLM, WRN, and RecQ4 are associated with premature aging and cancer predispos...

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Détails bibliographiques
Auteurs principaux: Rossi, Marie L., Ghosh, Avik K., Kulikowicz, Tomasz, Croteau, Deborah L., Bohr, Vilhelm A.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893255/
https://ncbi.nlm.nih.gov/pubmed/20451470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.04.003
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