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A Multiplex Calcium Assay for Identification of GPCR Agonists and Antagonists

Activation of G(q) protein-coupled receptors can be monitored by measuring the increase in intracellular calcium with fluorescent dyes. Recent advances in fluorescent kinetic plate readers and liquid-handling technology have made it possible to follow these transient changes in intracellular calcium...

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Autors principals: Liu, Ke, Southall, Noel, Titus, Steve A., Inglese, James, Eskay, Robert L., Shinn, Paul, Austin, Christopher P., Heilig, Markus A., Zheng, Wei
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893246/
https://ncbi.nlm.nih.gov/pubmed/20230302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2009.0245
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