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A Multiplex Calcium Assay for Identification of GPCR Agonists and Antagonists
Activation of G(q) protein-coupled receptors can be monitored by measuring the increase in intracellular calcium with fluorescent dyes. Recent advances in fluorescent kinetic plate readers and liquid-handling technology have made it possible to follow these transient changes in intracellular calcium...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Mary Ann Liebert, Inc.
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893246/ https://ncbi.nlm.nih.gov/pubmed/20230302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2009.0245 |
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