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Sequence embedding for fast construction of guide trees for multiple sequence alignment

BACKGROUND: The most widely used multiple sequence alignment methods require sequences to be clustered as an initial step. Most sequence clustering methods require a full distance matrix to be computed between all pairs of sequences. This requires memory and time proportional to N(2 )for N sequences...

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Bibliografiske detaljer
Main Authors: Blackshields, Gordon, Sievers, Fabian, Shi, Weifeng, Wilm, Andreas, Higgins, Desmond G
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893182/
https://ncbi.nlm.nih.gov/pubmed/20470396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-5-21
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