Ethanol inhibition of aspartyl-asparaginyl-β-hydroxylase in fetal alcohol spectrum disorder: Potential link to the impairments in central nervous system neuronal migration

Fetal alcohol spectrum disorder (FASD) is caused by prenatal exposure to alcohol and associated with hypoplasia and impaired neuronal migration in the cerebellum. Neuronal survival and motility are stimulated by insulin and insulin-like growth factor (IGF), whose signaling pathways are major targets...

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Bibliografiske detaljer
Main Authors: de la Monte, Suzanne M., Tong, Ming, Carlson, Rolf I., Carter, Jade J., Longato, Lisa, Silbermann, Elizabeth, Wands, Jack R.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893031/
https://ncbi.nlm.nih.gov/pubmed/19393862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2008.09.009
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