Extinction Training after Cocaine Self-Administration Induces Glutamatergic Plasticity to Inhibit Cocaine Seeking

Learning to inhibit drug seeking can be an important strategy for inhibiting relapse, and this can be modeled by extinguishing drug seeking in response to a drug-paired context. Rats were either extinguished or withdrawn without extinction training (abstinence) from cocaine self-administration, and...

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Main Authors: Knackstedt, Lori A., Moussawi, Khaled, Lalumiere, Ryan, Schwendt, Marek, Klugmann, Matthias, Kalivas, Peter W.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2010
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893028/
https://ncbi.nlm.nih.gov/pubmed/20534846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1244-10.2010
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