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mGlu5 Receptors and Relapse to Cocaine-Seeking: The Role of Receptor Trafficking in Postrelapse Extinction Learning Deficits

We have previously demonstrated that MTEP, an allosteric antagonist of mGlu5, infused into the nucleus accumbens attenuates relapse after abstinence from cocaine self-administration. MTEP infused into the dorsolateral striatum (dlSTR) does not alter relapse but has long-lasting effects on subsequent...

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Détails bibliographiques
Publié dans:Neural Plast
Auteurs principaux: Knackstedt, Lori A., Schwendt, Marek
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736983/
https://ncbi.nlm.nih.gov/pubmed/26881139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9312508
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