mGlu5 Receptors and Relapse to Cocaine-Seeking: The Role of Receptor Trafficking in Postrelapse Extinction Learning Deficits

We have previously demonstrated that MTEP, an allosteric antagonist of mGlu5, infused into the nucleus accumbens attenuates relapse after abstinence from cocaine self-administration. MTEP infused into the dorsolateral striatum (dlSTR) does not alter relapse but has long-lasting effects on subsequent...

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Bibliographische Detailangaben
Veröffentlicht in:Neural Plast
Hauptverfasser: Knackstedt, Lori A., Schwendt, Marek
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736983/
https://ncbi.nlm.nih.gov/pubmed/26881139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9312508
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