Antifibrotic Effects of CXCL9 and Its Receptor CXCR3 in Livers of Mice and Humans

BACKGROUND & AIMS: Fibrosis is the hallmark of chronic liver diseases, yet many aspects of its mechanism remain to be defined. Chemokines are ubiquitous chemotactic molecules that mediate many acute and chronic inflammatory conditions, and CXC chemokine genes colocalize with a locus previously s...

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Main Authors: WASMUTH, HERMANN E., LAMMERT, FRANK, ZALDIVAR, MIRKO MORENO, WEISKIRCHEN, RALF, HELLERBRAND, CLAUS, SCHOLTEN, DAVID, BERRES, MARIE-LUISE, ZIMMERMANN, HENNING, STREETZ, KONRAD L., TACKE, FRANK, HILLEBRANDT, SONJA, SCHMITZ, PETRA, KEPPELER, HILDEGARD, BERG, THOMAS, DAHL, EDGAR, GASSLER, NIKOLAUS, FRIEDMAN, SCOTT L., TRAUTWEIN, CHRISTIAN
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892869/
https://ncbi.nlm.nih.gov/pubmed/19344719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.03.053
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