Genetic Variants of Nogo-66 Receptor with Possible Association to Schizophrenia Block Myelin Inhibition of Axon Growth

In schizophrenia, genetic predisposition has been linked to chromosome 22q11 and myelin-specific genes are misexpressed in schizophrenia. Nogo-66 receptor 1 (NGR or RTN4R) has been considered to be a 22q11 candidate gene for schizophrenia susceptibility because it encodes an axonal protein that medi...

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Main Authors: Budel, Stéphane, Padukkavidana, Thihan, Liu, Betty P., Feng, Zeny, Hu, Fenghua, Johnson, Sam, Lauren, Juha, Park, James H., McGee, Aaron W., Liao, Ji, Stillman, Althea, Kim, Ji-Eun, Yang, Bao-Zhu, Sodi, Stefano, Gelernter, Joel, Zhao, Hongyu, Hisama, Fuki, Arnsten, Amy F. T., Strittmatter, Stephen M.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892845/
https://ncbi.nlm.nih.gov/pubmed/19052207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3828-08.2008
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