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Selective molecular potassium channel blockade prevents atrial fibrillation

BACKGROUND: Safety and efficacy limit currently available atrial fibrillation (AF) therapies. We hypothesized that atrial gene transfer would allow focal manipulation of atrial electrophysiology, and by eliminating reentry, would prevent AF. METHODS AND RESULTS: In a porcine AF model, we compared co...

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Bibliografski detalji
Glavni autori: Guy, Amit, Kikuchi, Kan, Greener, Ian D., Yang, Lizhu, Novack, Victor, Donahue, J. Kevin
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892844/
https://ncbi.nlm.nih.gov/pubmed/20479154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.911156
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