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Selective molecular potassium channel blockade prevents atrial fibrillation

BACKGROUND: Safety and efficacy limit currently available atrial fibrillation (AF) therapies. We hypothesized that atrial gene transfer would allow focal manipulation of atrial electrophysiology, and by eliminating reentry, would prevent AF. METHODS AND RESULTS: In a porcine AF model, we compared co...

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Bibliografiska uppgifter
Huvudupphovsmän: Guy, Amit, Kikuchi, Kan, Greener, Ian D., Yang, Lizhu, Novack, Victor, Donahue, J. Kevin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892844/
https://ncbi.nlm.nih.gov/pubmed/20479154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.911156
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