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Mixed lineage leukemia: a structure-function perspective of the MLL1 protein

Several acute lymphoblastic and myelogenous leukemias are correlated with alterations in the human Mixed Lineage Leukemia protein-1 (MLL1) gene. MLL1 is a member of the evolutionarily conserved SET1 family of histone H3 lysine 4 (H3K4) methyltransferases, which are required for the regulation of dis...

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Detalhes bibliográficos
Main Authors: Cosgrove, Michael S., Patel, Anamika
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892832/
https://ncbi.nlm.nih.gov/pubmed/20236310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07609.x
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