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IL-1R signaling within the CNS regulates CXCL12 expression at the blood-brain barrier and disease severity during experimental autoimmune encephalomyelitis
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) characterized by disruption of the blood-brain barrier (BBB). This breach in CNS immune privilege allows undeterred trafficking of myelin-specific lymphocytes into the CNS where they induce demyelination. Although t...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892701/ https://ncbi.nlm.nih.gov/pubmed/19535637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802258 |
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